Protein Info for Echvi_0540 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 32 to 475 (444 residues), 252.2 bits, see alignment E=4.9e-79 PF02321: OEP" amino acids 66 to 264 (199 residues), 60.5 bits, see alignment E=9.6e-21 amino acids 289 to 474 (186 residues), 81.5 bits, see alignment E=3.4e-27

Best Hits

KEGG orthology group: None (inferred from 69% identity to shg:Sph21_1488)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein, NodT family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FSA7 at UniProt or InterPro

Protein Sequence (477 amino acids)

>Echvi_0540 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family (Echinicola vietnamensis KMM 6221, DSM 17526)
MIKRIIYISLGAVFMTLAITSCKTPSVVEKTPDTAVPEHFDSASDTANTARVKWQDFFTD
PYLSALIDTALNNNQELNIILQEIAVSKNEIQAKKGEYLPSVDIRAGAGLDKVGRYTSRG
ASEATTDIEPGREMPEPLPDFMVGAFASWEADIWGKLHNAKRAAVARYLSSVEGKNFMVT
NLIAEIANAYYELLALDNQLAIVKRNIKIQHDALEIVKLQKSAAKATELAVKKFEAEVFH
TKSLQYDIQQKITETENKINFLVGRFPQPVIRDSEAFIDLVPKQVQAGLPAQLLDNRPDI
RQAEMELAAAKLDVKVAKARFYPSLGISAGIGFQAFNPSYLIKTPESLLYSLAGDLAAPL
INRKEIKATYKSANSKQIQAVYNYEKTILNAYVEVANQLAKIKNLEKSYGLKAKEVEALT
TSINISGDLFKSARADYMEVLMTQRDALESKFDLVETKMQQMNAFVNMYQALGGGWN