Protein Info for Echvi_0408 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1055 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF13715: CarbopepD_reg_2" amino acids 34 to 116 (83 residues), 70 bits, see alignment 2.9e-23 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 34 to 1055 (1022 residues), 908.9 bits, see alignment E=5.2e-277 PF13620: CarboxypepD_reg" amino acids 34 to 93 (60 residues), 36.8 bits, see alignment 8.1e-13 PF07715: Plug" amino acids 124 to 232 (109 residues), 74.7 bits, see alignment E=1.7e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 208 to 238 (31 residues), 68.6 bits, see alignment (E = 3.1e-23) PF00593: TonB_dep_Rec_b-barrel" amino acids 446 to 819 (374 residues), 69.1 bits, see alignment E=1.5e-22

Best Hits

KEGG orthology group: None (inferred from 59% identity to phe:Phep_2600)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FVB4 at UniProt or InterPro

Protein Sequence (1055 amino acids)

>Echvi_0408 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MNFIIEAMKHFYKLFFLMLFFIWASDGFAQEIILKGTVADGESEEGLPGVSILLKGTTIG
TVTDAMGNYNIKVPDSTGTLIFSFIGYRTQEIPIDGRAVMDIVMELDVASLSEVVVVGYG
TTTKKDLTGSIETVEIEDVQKAPVKSFDEALAGRVAGVMVSGNDGQPGSNNNIIIRGVGS
ITGSTAPLYVVDGFPMEDSYANTLNINDIESMTVLKDASATAIYGARGANGVIIITTKRG
KQGAPEISYNMYYGISQNPKPIKLMDAYQFVKYQSELNPEVADKIYFTNGKSLEDYRNVE
SIDLQDQIYQNAPILNHDISIRGGNGKTNYSLSGNILNQDGIAVNSGFRRYSGRITLDQE
VNKKINVGADIVYSSEKTHGAIMTQSSSNSLTYGNLSLMAAVWGFRPVAGENENVMDELF
DPTIPSTDFRVNPILSAKNEHRITAVNSFRANGFLEYAIVPELTLKLAGGINNIMVRREG
FFNSLTTAGNDRRDQKQNGFIYFRPVSNWNNTNTLTFKKTYNNIHSLNAVVGTVVQKQGD
GNYGFSAIQVLNEGTAIDGLDEAAENFGTSGSSSWGLASFLGRLNYSYKSKYMLTSSVRY
DGSSKFAPGNRWGFFPSAALAWRMSEENLLKGISFISDAKLRLSHGATGNNRVSDFAYLS
TLSIPRSGGYSFNNGKPTRGALLENYGNPNLKWETTVQTDIGYDLEVLEGRVEITLDVYR
KMTKNVLLNADLPYSTGLTNIYNSASAYKNIGKIRNEGLEFTLNTINIHKDDFEWRTNFN
ISFNQNEVMELNEGQTSLLENVRFDQYFSNTHPYIAQVGQPIGQMYGLIWDGVYQYEDFD
QVLGEYVLKDNIPSNGQPRTNIQPGDIKYRDINGDLVVNEMDFAVIGRGNPIHTGGFNNN
FNYKGFDLNIFFQWSYGNDIINANRLFFEGNARNLISLNQYATYEDRWTPENPTNEHFRT
AGKKDTWYTSRVVEDGSFLRLKTVSLGYNFNDRVLNKIRLKSLRLYASAQNLYTWTNYSG
SNPDVSTRHSALTPGFDFASYPLARTLTVGLSTTF