Protein Info for Echvi_0130 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Predicted metal-dependent hydrolase with the TIM-barrel fold

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07969: Amidohydro_3" amino acids 74 to 546 (473 residues), 327.9 bits, see alignment E=1.8e-101 PF01979: Amidohydro_1" amino acids 221 to 545 (325 residues), 31.1 bits, see alignment E=1.5e-11

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 58% identity to mtt:Ftrac_1027)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FT03 at UniProt or InterPro

Protein Sequence (546 amino acids)

>Echvi_0130 Predicted metal-dependent hydrolase with the TIM-barrel fold (Echinicola vietnamensis KMM 6221, DSM 17526)
MTKMKRFHTILFGIILLFSACAKKENVDLIVHNGLIYTVNGAFEQAEAFAVKDGKFIAVN
SSETILKKYSAPNIMDLKGKFVYPGLIDAHTHFYRYGTGLKVADLTGITSFEALVKTVKA
HRKAHPNQAWVLGRGWDQNLWPEKSFPEKSLLDEAFPNTPVLLTRIDGHAAIANQKALDM
GEITATTDILGGKIILQNGEPTGVLIDNAIGMVSSKIPEISTAESRQALLDAQENCFAVG
LTTVADAGLDKPIIDLMESMQKEGDLKMRIYAMVNPTEENMAYYFEKGPFQNESLTVRSF
KIYGDGALGSRGASLLAPYHDAPDELGFLLNTPENFLSLAEDIHDHGFQMNTHCIGDSAN
RTLLNIYAKVLMKENDQRWRIEHAQVVHPQDVEKFATYHIIPSVQPTHATSDMYWAEDRL
GEERVKHAYIYKDLLEQNGLIALGSDFPVESINPLFGFHAAVARQDANNWPTDGFQTENS
LTRQEALKGMTIWAAYANFEENLKGSIESGKLADFIITSRDLMTAPHENLREIKVEATYI
GGEKVY