Protein Info for EX28DRAFT_3321 in Enterobacter asburiae PDN3

Annotation: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00497: SBP_bac_3" amino acids 38 to 254 (217 residues), 110.1 bits, see alignment E=6e-36

Best Hits

Swiss-Prot: 94% identical to YHDW_ECO57: Putative amino-acid ABC transporter-binding protein YhdW (yhdW) from Escherichia coli O157:H7

KEGG orthology group: K09969, general L-amino acid transport system substrate-binding protein (inferred from 98% identity to enc:ECL_04652)

Predicted SEED Role

"Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (341 amino acids)

>EX28DRAFT_3321 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain (Enterobacter asburiae PDN3)
MKKTMIASLAAAGMLFAVAGQAHAGTTLDAVKKKGFVQCGISDGLPGFSYADANGKFTGI
DVDVCRGVAAAVFGDDSKVKYTPLTAKERFTALQSGEVDMLSRNTTWTSSRDAGMGMSFT
GVTYYDGIGFLTHNKAGLKSAKELDGATVCIQAGTDTELNVADYFKANNMKYTPVTFDRS
DESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVLPEVISKEPLGPVVRRGDEDWFS
IVRWTLFAMLNAEEMGINSKNVDEKAAKPSNPDMAHLLGKEGDFGKDLKLDNKWAYNIIK
QVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGIQYAPPVR