Protein Info for EX28DRAFT_3255 in Enterobacter asburiae PDN3

Annotation: ABC-type (unclassified) transport system, ATPase component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 TIGR04406: LPS export ABC transporter ATP-binding protein" amino acids 3 to 241 (239 residues), 398.6 bits, see alignment E=4e-124 PF00005: ABC_tran" amino acids 20 to 166 (147 residues), 124.1 bits, see alignment E=6.6e-40 PF12399: BCA_ABC_TP_C" amino acids 215 to 239 (25 residues), 32.7 bits, see alignment (E = 4.5e-12)

Best Hits

Swiss-Prot: 95% identical to LPTB_ECOL6: Lipopolysaccharide export system ATP-binding protein LptB (lptB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K06861, lipopolysaccharide export system ATP-binding protein [EC: 3.6.3.-] (inferred from 99% identity to enc:ECL_04583)

MetaCyc: 96% identical to LPS export ABC transporter ATP-binding protein (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-51 [EC: 7.5.2.5]

Predicted SEED Role

"Lipopolysaccharide ABC transporter, ATP-binding protein LptB" in subsystem KDO2-Lipid A biosynthesis

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>EX28DRAFT_3255 ABC-type (unclassified) transport system, ATPase component (Enterobacter asburiae PDN3)
MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNI
IIDDEDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRNDLTSEQRQDRANE
LMEEFHIEHLRDSLGQALSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRII
EHLRDSGLGVLITDHNVRETLAVCERAYIVSQGNLIAHGTPQQILEDDHVKRVYLGEDFR
L