Protein Info for EX28DRAFT_3128 in Enterobacter asburiae PDN3

Annotation: Bacteriophage replication gene A protein (GPA)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 PF05840: Phage_GPA" amino acids 139 to 453 (315 residues), 404.5 bits, see alignment E=3.1e-125 PF23343: REP_ORF2-G2P" amino acids 346 to 449 (104 residues), 32.6 bits, see alignment E=8.1e-12

Best Hits

Swiss-Prot: 73% identical to VPA_BP186: Replication gene A protein (A) from Escherichia phage 186

KEGG orthology group: None (inferred from 72% identity to ent:Ent638_3505)

Predicted SEED Role

"Phage replication protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (729 amino acids)

>EX28DRAFT_3128 Bacteriophage replication gene A protein (GPA) (Enterobacter asburiae PDN3)
MATSFAYPWNAPRSAIASPYLTHAQQQRRDRLFAALQQARIALSQQPDCVRFEIWRTVDA
LEQHRGSPQANAFLIRFCKRMLPRLRRVSERYACTGLHDEVSRAVFDGHFDTQLLQYLAS
RMVELVARYNRLPDMTRADIDLLAADIASFIRGELANINDAEMGEYQTLYVWYQRAGLIA
RQFNVSPPHWERVSKTFFNKDDVAAAVIRMFSEAWWRGRLRRIAAAWREHLQIALGNVSK
QRAAYASKRCVTEWREQKRRTREFLKGMELEDEEGNRISLIEKYDSSVANPAIRRCELMT
RIRGFENICEALGYVGEFYTLTAPAQYHATLKSGFPNAKWNGASPADTQTYFTRLWARIR
AKLHRDGHRIFGIRVAEPHHDGTPHWHMLMFMLPEDVECVRRIIGDYARQDAAAELQSES
ARQARFHADAIDPQKGSATGYIAKYISKNIDGYALNGETDSESGGLLKETASAVSAWAGR
WHIRQFQFIGGAPVTVYRELRRLVDTEAARGLSVEFAAVQEAADAGDWAGYVTAQGGPFV
RRDDLQVRTLYEPRAGFNQYGEETVRIRGVYDSAVGAGSPVLTRLTQWKIVPKRAADLKD
APVASRSSVNNCTQADLSQPLSRRARRALTERIKFIRPGATAPVVFASDPQNGVPEKVID
EIRLATGIAISRAEALHLMAGGISRFNDKWCRGAADGSLFPAPCSYQQKARKILERIGYL
TDLFAQRAR