Protein Info for EX28DRAFT_3003 in Enterobacter asburiae PDN3

Annotation: holo-ACP synthase CitX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 179 TIGR03124: holo-ACP synthase CitX" amino acids 11 to 174 (164 residues), 192.7 bits, see alignment E=2.1e-61 PF03802: CitX" amino acids 11 to 174 (164 residues), 180.6 bits, see alignment E=1.1e-57

Best Hits

Swiss-Prot: 36% identical to CITX_VIBCH: Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase (citX) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K05964, holo-ACP synthase [EC: 2.7.7.61] (inferred from 92% identity to enc:ECL_04294)

Predicted SEED Role

"Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.61)" (EC 2.7.7.61)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.61

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (179 amino acids)

>EX28DRAFT_3003 holo-ACP synthase CitX (Enterobacter asburiae PDN3)
MTLATPVRAGVSLDELLAAKERRAARQADMLEHYQQPVISLTLVTPGEIKDSLRYRNTMG
VALQMCDQLLWENRWPVLDRQVLWLPTGPEALWCVAHPAAEIKAHCADLEQTHPLGRLWD
LDVISPQHGHVGRQSLGANLRRCLICDEPAHVCSRSRKHPVELVVSRVEKTIDDWFARD