Protein Info for EX28DRAFT_2433 in Enterobacter asburiae PDN3

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 727 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07715: Plug" amino acids 73 to 170 (98 residues), 55.7 bits, see alignment E=6.5e-19 TIGR01783: TonB-dependent siderophore receptor" amino acids 75 to 727 (653 residues), 392.4 bits, see alignment E=2.3e-121 PF00593: TonB_dep_Rec_b-barrel" amino acids 239 to 695 (457 residues), 118.6 bits, see alignment E=6.9e-38

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 93% identity to enc:ECL_03171)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (727 amino acids)

>EX28DRAFT_2433 TonB-dependent siderophore receptor (Enterobacter asburiae PDN3)
MNNTIMHKTLLALAVGAATHSAFAADDQKEDTLVVQAAPASDFKPGGDQLVPAFLDGQVA
NGGRMGMLGQQNAMDVPFNIISYTSKLVEDQQAKTIADVVANDAGVQFVQGYGNSAETYR
IRGLKFDGDDMTFGGLSGVLPRQVVDTQMVDRIEIFKGANSLMNGAASSGVGGMINLEPK
HAGELPQAKVGVDYTSDSQFGTTLDAGRRYGDSDQFGARVNLVHREGETGNANDRRRTTL
LSTGLDYTGDRFRTSLDLGYQKKTFHGSPTSVNISAVDFVPEPPKNDRNFSQKWAYSNIE
NEFGMWRSEYDITDGWTAYTGLGAQHAHEEGIYSAPKLVDKSGKATVSRLDTNRISDSVS
GMAGVRGNFTTGFVSHKVNVGYSAMTKNEKIAWKMSAAKDNPITNIYHNTGVDMPDSTNF
NGSGGKYSDPLTSGRTRTQGWLLSDTLGVLDDKLLFTAGARHQKVVVRGYNKVTGAENTA
DGFDGSRWMPTYGVVYKPWEAISLYANHTEALQPGKTAPNTATNYGQSTGIVHSKQNEVG
IKADFGRVGGSLALFEIKMPSAILDDSGHYGLDAEQRNRGVELNVFGEPMLGMRLNASAT
WLQAELTKTKNGVNQGNDAIGIPNFYAVVGAEYDIKPVDGLTATARVNHSGAQYADLANT
KKLDSYTTLDLGMRYRFAVNHNENQMTVRAGIDNVTNENYWASVDDSGTYITQGEPRTFK
VSVGYAF