Protein Info for EX28DRAFT_1657 in Enterobacter asburiae PDN3

Annotation: drug resistance transporter, Bcr/CflA subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 40 to 61 (22 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 131 to 154 (24 residues), see Phobius details amino acids 161 to 180 (20 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details amino acids 237 to 259 (23 residues), see Phobius details amino acids 271 to 294 (24 residues), see Phobius details amino acids 300 to 322 (23 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 362 to 380 (19 residues), see Phobius details signal peptide" amino acids 28 to 29 (2 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 5 to 380 (376 residues), 420 bits, see alignment E=6.1e-130 PF07690: MFS_1" amino acids 14 to 343 (330 residues), 160.9 bits, see alignment E=4e-51 PF00083: Sugar_tr" amino acids 37 to 120 (84 residues), 39.9 bits, see alignment E=2.6e-14

Best Hits

Swiss-Prot: 78% identical to YDHC_ECOLI: Inner membrane transport protein YdhC (ydhC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to enc:ECL_02343)

MetaCyc: 78% identical to purine nucleoside transporter PunC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-631

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>EX28DRAFT_1657 drug resistance transporter, Bcr/CflA subfamily (Enterobacter asburiae PDN3)
MQPRNGFLVWLGGLSVLGFLATDMYLPAFAAMQEDLQTPAAAISASLSLFLAGFAFAQLL
WGPLSDRFGRKPVLLLGLAIFAVGCLGMLWVRDATWLLVLRFIQAVGVCAAAVTWQALVT
DYYPANRTNRIFATIMPLVGLSPALAPLLGSWILAHFDWQAIFATLFAITLVLMLPAFAL
KPAHKKEAHADAKPITFTSLLSTKAYRGNVLIYAACSASFFAWLTGSPFILHDMGYSPAA
IGLSYVPQTIAFLVGGYGCRAALQKWEGQQMLPWLLVLYALSVIGTWAVGFIPGAGLAEI
LIPFCVMAVANGAIYPIVVAQALRPFPQATGRAAALQNTLQLGLCFLASLVVSALIATPL
LTTTSVMLVTVALAVLGYRMQAAAQRDQANRTQVETSHA