Protein Info for EX28DRAFT_1256 in Enterobacter asburiae PDN3

Annotation: methyl-accepting chemotaxis sensory transducer with TarH sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details PF02203: TarH" amino acids 15 to 188 (174 residues), 127.6 bits, see alignment E=1e-40 PF12729: 4HB_MCP_1" amino acids 31 to 198 (168 residues), 31.5 bits, see alignment E=2.7e-11 PF00672: HAMP" amino acids 225 to 276 (52 residues), 43.6 bits, see alignment 6.2e-15 PF00015: MCPsignal" amino acids 339 to 496 (158 residues), 193.5 bits, see alignment E=5.5e-61

Best Hits

Swiss-Prot: 77% identical to MCP3_ECOLI: Methyl-accepting chemotaxis protein III (trg) from Escherichia coli (strain K12)

KEGG orthology group: K05876, methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor (inferred from 95% identity to enc:ECL_02058)

Predicted SEED Role

"Methyl-accepting chemotaxis protein III (ribose and galactose chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (563 amino acids)

>EX28DRAFT_1256 methyl-accepting chemotaxis sensory transducer with TarH sensor (Enterobacter asburiae PDN3)
MDNTTSMQAQRKLSFLHHIRLVPLFSSILGGIILLFALSSGLAGYFLLQADNDQQDVTSE
IQVRMGLSNSSNHLRTARINLIHAGAASRIAEMDAMKQNISEAETRIKQSQESFTAYMNR
AVRTAEGAALDEDLKARYDAYIAGMQPMVKFAKNGMFEAIINHENETARPLDDAYNAVLL
KAIKIRTERANALTAQAHSRTQLGLMFMVGAFALALVLTAMTFVVLRRTVINPLQRAAKR
IENIAKGDLTMPDDVAGRSEIGRLTRDLQTMQHSLENTVGTVRQGAEEIYRGTSEISAGN
TDLSSRTEQQAAAIEQTAASMEQLTATVKQNADNAHHASKLAEDASGKASRGGQMVSGVV
KTMGNISTSSKKISEITAVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAS
RSANAAKEIESLINESVSLIDQGSGEVVAAGNTMNEIVEAVKRVTDIMLEIAAASDEQSR
GIVQVSQAISEMDKVTQQNASLVEEASAAAASLEEQGARLTEAVGAFRLSGAKSGRVVTS
APVAKNAPLRPAATVSGDNWETF