Protein Info for EX28DRAFT_0887 in Enterobacter asburiae PDN3

Annotation: Bacteriophage replication gene A protein (GPA)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 785 PF05840: Phage_GPA" amino acids 151 to 479 (329 residues), 371.1 bits, see alignment E=4.4e-115 PF23343: REP_ORF2-G2P" amino acids 380 to 475 (96 residues), 28.7 bits, see alignment E=1.3e-10

Best Hits

Swiss-Prot: 74% identical to VPA_BPP2: Replication gene A protein (A) from Escherichia phage P2

KEGG orthology group: None (inferred from 74% identity to ecv:APECO1_4464)

Predicted SEED Role

"Phage replication protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (785 amino acids)

>EX28DRAFT_0887 Bacteriophage replication gene A protein (GPA) (Enterobacter asburiae PDN3)
MNAWGSNVWTPLNSMSIESRGRIAPSPPPPFLKGASDSFVGAYPWNNVTKEAIGRDRPLT
RAELRQVQGVLNRIDRLPFFLQTLFTSRYNFIRRKKSPLGGLYFLKNTFERKLLPRLERV
NELCGMNESASIGFLSARDEYARLPDMNDKELRKFASRIASQLWSRYEELSDAWAHAHGG
KETLFTDEAQAHLYGKVAGVARAFNLTPMYWKKYRKGQITIRQAFSAISRLIKDEWWVNQ
LKAQRMRWREALLIAAGEVNKDRSPYASKMAIRDVHARRLANLEYLKSCELENKVTGERI
DLISKVMGSISNPEIRRMELMNTIAGIERYATSVGDVGMFITLTTPSKYHPTRQIGKGES
KTVQLNHGWNETAFTPKDGQRYLCRIWSLMRTAFKDNDLEVYGMRVVEPHHDGTPHWHMM
LFCKPGQRKAINEIMRRYALKEDGHEKGAAKQRFESRHLNQGGAAGYIAKYIAKNIDGYA
LDGQLDHDTGKPLKDTAAAVTAWASTWRIPQFKPIGLPTMGAYRELRKLPRGVSIASEFD
DRVEAARVAADEGDFERYIIAQGGANMPRDAQAVRVARKVTDEVNDYEEDIERVVGIYAP
HLGAHRVHVTRTAEWRIVPKVLAVEPLTLKSGSAAPRSPVNNCGKLTGGGDPVMTHTPSE
QAAAVLNLIERGVIGWNEPDVVKVLNGALKAGAPRKHRQQRSNAPLKTSEQAPSARMTKP
ERDRVAKIRFDLAQEGITPERWELDALARGATVIYGDKKFKYRAADRWPGFSMQEEISEK
QPSPL