Protein Info for EX28DRAFT_0603 in Enterobacter asburiae PDN3
Annotation: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 88% identical to RCSA_ECOLX: Transcriptional regulatory protein RcsA (rcsA) from Escherichia coli
KEGG orthology group: K07781, LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor (inferred from 99% identity to enc:ECL_03233)Predicted SEED Role
"Colanic acid capsular biosynthesis activation accesory protein RcsA, co-regulator with RcsB"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (207 amino acids)
>EX28DRAFT_0603 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain (Enterobacter asburiae PDN3) MSTIIMDLCSYTRLGLTGYLASRGVKKRDINDAHTVDELAAACDELKPGVVFINEDCFIH DPANSQHIKQIINQHPKTLFIVFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDY LNKEVKNVGAVNLPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI KTHNKQVIYHVVRLTDNVTNGIFVNMR