Protein Info for EX28DRAFT_0573 in Enterobacter asburiae PDN3

Annotation: Lysine/ornithine N-monooxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 PF13434: Lys_Orn_oxgnase" amino acids 2 to 332 (331 residues), 372.8 bits, see alignment E=1.6e-115 PF13738: Pyr_redox_3" amino acids 84 to 201 (118 residues), 40.9 bits, see alignment E=1.6e-14

Best Hits

Swiss-Prot: 63% identical to IUCD_ECOLX: L-lysine N6-monooxygenase (iucD) from Escherichia coli

KEGG orthology group: K03897, lysine N6-hydroxylase [EC: 1.14.13.59] (inferred from 94% identity to enc:ECL_03319)

MetaCyc: 63% identical to L-lysine 6-monooxygenase subunit (Escherichia coli K-12)
L-lysine 6-monooxygenase (NADPH). [EC: 1.14.13.59]

Predicted SEED Role

"L-lysine 6-monooxygenase [NADPH] (EC 1.14.13.59), aerobactin biosynthesis protein IucD @ Siderophore biosynthesis protein, monooxygenase" (EC 1.14.13.59)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>EX28DRAFT_0573 Lysine/ornithine N-monooxygenase (Enterobacter asburiae PDN3)
MKTYDFIGIGIGPFNLSIAALAEGLDGFSSLFLERKPHFSWHPGMMVPDCHMQTSFLKDL
VSAVEPTNRHSFLNYLVQRKKFYRFLTTEQRTVSREEFADYLCWAAENLTNLSFSQQVQQ
VSFDDKSGLFEVMTQRDRFLARHVCVGIGKQINLPDCVTVQDDTCFHASEMMLRTPDLAG
KRVTVVGGGQSGADLFLNIFRGEWGQPLSLNWVSRRNNYNALDEAAFANEYFTPEYVDSF
STLGEEARRQMLHEQKMTSDGITTESLLAIYRAMYHRFEVLREKPWAHLLPSRSVTALTR
QENGHRLSIQHHLDGGREQLESDVVIFATGYRAVQPAFLAPLSHRLHMDTDEAFCINNDF
TLEWDGPQSNRLFAVNAGMHRLGIAEPQLSLMAWRAARILNRAHADEPFELATTPGVIHW
RTTASTDSSPVFKSLAKTTEY