Protein Info for EX28DRAFT_0403 in Enterobacter asburiae PDN3

Annotation: Protein of unknown function (DUF1228)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 22 to 23 (2 residues), see Phobius details amino acids 31 to 55 (25 residues), see Phobius details amino acids 71 to 88 (18 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 205 to 226 (22 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 267 to 284 (18 residues), see Phobius details amino acids 290 to 311 (22 residues), see Phobius details amino acids 323 to 348 (26 residues), see Phobius details amino acids 354 to 372 (19 residues), see Phobius details PF07690: MFS_1" amino acids 12 to 339 (328 residues), 38.5 bits, see alignment E=6.9e-14 PF06779: MFS_4" amino acids 13 to 370 (358 residues), 281.3 bits, see alignment E=1.5e-87

Best Hits

KEGG orthology group: None (inferred from 94% identity to enc:ECL_03463)

Predicted SEED Role

"Possible MFS Superfamily transporter precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>EX28DRAFT_0403 Protein of unknown function (DUF1228) (Enterobacter asburiae PDN3)
MALRIALSGFVVLVVAMGIGRFAFTPQVPLMIAAGQLTLTSAGLVAAMNYLGYLVGAWDA
MRAHRFVETRLWLGITGAVALTLLSAAADNAVVHGLLRFVIGCMSGWSMVLIAAWTNERL
GQLGKPGLSSAVFAGPGAGIALSGLLAVYIQAKSLSAGAAWQIYGVLALVLIVLVARYLP
RSGQLHRPGTAPEPLVLTADLKRLVWSYSLAGFGYILPATFLSQMAAVRFPGSLFAQFVW
PIFGIAAVVGIALSILLRHTSTANRRLAIVLWLQGTGVLAAWLLPGIGGLLTGGLLVGGG
FLCAVQLSLLYGRELAPNHTRYMAGLLTTGYAIGQLIGPMTSALSTWLTHRLEPALGLAG
VALFVGGALVWNRHAERQQQLQ