Protein Info for ECD_04241 in Escherichia coli BL21

Annotation: DUF1212 family inner membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 114 to 135 (22 residues), see Phobius details amino acids 141 to 158 (18 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 195 to 215 (21 residues), see Phobius details amino acids 227 to 251 (25 residues), see Phobius details PF06738: ThrE" amino acids 11 to 249 (239 residues), 231.9 bits, see alignment E=4e-73

Best Hits

Swiss-Prot: 100% identical to YJJP_SHIFL: Inner membrane protein YjjP (yjjP) from Shigella flexneri

KEGG orthology group: None (inferred from 100% identity to eco:b4364)

Predicted SEED Role

"FIG023911: putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>ECD_04241 DUF1212 family inner membrane protein (Escherichia coli BL21)
MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMDSVESSISSNAIVLTTI
KDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGVEKRFSQIQPLRYPRWLVA
LMVGLSCACFCKLNNGGWDGAVITFFASTTAMYIRQLLAQRHLHPQINFCLTAFAATTIS
GLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMFKGHINTGLARWAIASLLTLATC
VGVVMALTIWGLRGWV