Protein Info for ECD_03818 in Escherichia coli BL21

Annotation: essential cell division protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 transmembrane" amino acids 29 to 54 (26 residues), see Phobius details TIGR02223: cell division protein FtsN" amino acids 1 to 315 (315 residues), 389.5 bits, see alignment E=6.3e-121 PF05036: SPOR" amino acids 246 to 313 (68 residues), 62.9 bits, see alignment E=1.5e-21

Best Hits

Swiss-Prot: 100% identical to FTSN_ECOLI: Cell division protein FtsN (ftsN) from Escherichia coli (strain K12)

KEGG orthology group: K03591, cell division protein FtsN (inferred from 100% identity to eco:b3933)

MetaCyc: 100% identical to cell division protein FtsN (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Cell division protein FtsN" in subsystem Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>ECD_03818 essential cell division protein (Escherichia coli BL21)
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKE
ESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQ
LLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQ
QQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTA
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADST
LNRLKMAGHTNCIRLAAGG