Protein Info for ECD_03611 in Escherichia coli BL21

Annotation: phosphate ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 75 to 100 (26 residues), see Phobius details amino acids 112 to 142 (31 residues), see Phobius details amino acids 161 to 186 (26 residues), see Phobius details amino acids 227 to 250 (24 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details TIGR02138: phosphate ABC transporter, permease protein PstC" amino acids 18 to 311 (294 residues), 307.2 bits, see alignment E=5e-96 PF00528: BPD_transp_1" amino acids 96 to 303 (208 residues), 55.7 bits, see alignment E=2.7e-19

Best Hits

Swiss-Prot: 100% identical to PSTC_ECO57: Phosphate transport system permease protein PstC (pstC) from Escherichia coli O157:H7

KEGG orthology group: K02037, phosphate transport system permease protein (inferred from 100% identity to eco:b3727)

MetaCyc: 100% identical to phosphate ABC transporter membrane subunit PstC (Escherichia coli K-12 substr. MG1655)
ABC-27-RXN [EC: 7.3.2.1]; 7.3.2.1 [EC: 7.3.2.1]

Predicted SEED Role

"Phosphate transport system permease protein PstC (TC 3.A.1.7.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (TC 3.A.1.7.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>ECD_03611 phosphate ABC transporter permease (Escherichia coli BL21)
MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIISSWPSIQKFGLAFLWTK
EWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTELAPGWLKRPLGIAIELLA
AIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGALFSGPAFGIGILAAGVILAIM
IIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGIMLGLGRALG
ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHVAALMELGLILFVITFI
VLAASKFMIMRLAKNEGAR