Protein Info for ECD_03448 in Escherichia coli BL21

Annotation: Rhs protein with putative toxin 55 domain; putative polysaccharide synthesis/export protein; putative neighboring cell growth inhibitor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 PF20148: DUF6531" amino acids 46 to 107 (62 residues), 55.7 bits, see alignment E=5.1e-19 TIGR03696: RHS repeat-associated core domain" amino acids 98 to 160 (63 residues), 79.9 bits, see alignment E=7.8e-27 PF15606: Ntox34" amino acids 211 to 285 (75 residues), 145.9 bits, see alignment E=3.2e-47

Best Hits

KEGG orthology group: None (inferred from 100% identity to ebd:ECBD_0137)

Predicted SEED Role

"core protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>ECD_03448 Rhs protein with putative toxin 55 domain; putative polysaccharide synthesis/export protein; putative neighboring cell growth inhibitor (Escherichia coli BL21)
MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVTSGHPVNPLLGAKVLPG
ETDLALPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADIRLPGQQYDEESGLYYNRH
RYYDPLQGRYITQDPIGLKGGWNFYQYPLNPVTNTDPLGLEVFPRPFPLPIPWPKSPAQQ
QADDNAAKALTKWWNDTASQRIFDSLILNNPGLALDITMIASRGNVADTGITDRVNDIIN
DRFWSDGKKPDRCDVLQELIDCGDISAKDAKSTQKAWNCRHSRQSNDKKR