Protein Info for ECD_03436 in Escherichia coli BL21

Annotation: putative regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 PF02311: AraC_binding" amino acids 26 to 132 (107 residues), 38.4 bits, see alignment E=1.5e-13 PF12833: HTH_18" amino acids 184 to 263 (80 residues), 69.1 bits, see alignment E=4.9e-23 PF00165: HTH_AraC" amino acids 226 to 260 (35 residues), 33.3 bits, see alignment 6.1e-12

Best Hits

KEGG orthology group: None (inferred from 98% identity to ect:ECIAI39_4096)

Predicted SEED Role

"Putative arylsulfatase regulatory protein" in subsystem Alkanesulfonate assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>ECD_03436 putative regulatory protein (Escherichia coli BL21)
MLELSMTLPIKVQNGGLFISRGVGRHPARRLESWEIIFVEKGRLTIQEEERIFLIDAGES
LLLWPNRQHVGVEDFPADLKFYWLHFEVKAPDSDPRWLTHLSVPQQTKVVDPQALVALFR
QFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAGTTLAWKAQKLIRTQYHRPLS
TALLARELYCNADYLGRVYRRVFHLTLTEAIHRQRVREAEKLLISEARSLTEVAALCGFN
DVGYFRQIFRKHTGLTPAAWKRRYSKEHINS