Protein Info for ECD_02046 in Escherichia coli BL21
Annotation: DUF4132 domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 97% identical to YEHI_ECOLI: Uncharacterized protein YehI (yehI) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 100% identity to ebr:ECB_02046)Predicted SEED Role
"Molybdate metabolism regulator"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1210 amino acids)
>ECD_02046 DUF4132 domain-containing protein (Escherichia coli BL21) MDKELPWLADNAQLELKYKKGKTPLSHRRWPGEPVSVITGSLIQTLGDELLQKAEKKKNI VWRYENFSLEWQSAITQAINLIGEHKPSVPAQTMAALACIAQNDSQQLLDEIVQQEGLEY ATEVVIARQFIARCYESDPLVVTLQYQDEDYGYGYRSETYNEFDLRLRKHLSLAEESCWQ RCADKLIAALPGITKVRRPFIALILPEKPEIANELVGLECPRTHFHSKEWLKVVANDPTA VRKLEHYWSQDIFSDREASYMSHENHFGYAACAALLREQGLAAIPRLAMYAHKEDCGSLL VQINHPQVIRTLLLVADKNKPSLQRVAKYHKNFPHATLAALAELLALTEPPARPGYPIIE DKKLPAQQKARDEYWRTLLQTLMASQPQLAEEVMQWLSTQARAVLNSYLSAPPKPVIDST DNSNLPEILVSPPWRSKKKMTAPRLDLAPLELTPQVYWQPGEQERLAATESARYFSTESL AQRMEQKSGRVVLQELGFGDDVWLFLNYILPGKLDAARNSLIVQWHYYQGRVEEILNGWN SPEAQLAEQALRSGHIEALINIWENDNYSRYRPEKSVWNLYLLAQLPREMALTFWLRINE KKHLFAGEDYFLSILGLDALPGLLLAFSHRPKETFPLILNFGATELALPVARVWHRFAGQ RNLARQWILQWPEHTATALIPLVFVKPCDNSEAALFALRLLYEQGHSELLQTVANRWDRA DMWPALEKILTQNPMEIYPARIPKAPDFWHPQMWSRPRLITNNQTVTNDALEIIGEMLRF TQGGRFYSGLEQLKTFCQPQTLAAFAWDLFTAWQQAGAPAKDNWTFLALSLFGDESTARD LTTQILAWPQEGKSARAVSGLNILTLMNNDMALIQLHHISQRAKSSSLRENAAEFLQVVA ENRGLSQEELADRLVPTLGLDDPQALIFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPR LRADDDQLKAPEALARLKGLKKDATQVSKNLLPRLEAALRTIRRWSLADFHTLFVNHPFT RLVTQRLIWGVYPANEPRCLLNAFRVAAEGEFCNAQDEPIGLPADALIGIAHPLEMTAEM RSEFAQLFADYEIMPPFRQLSRRTVLLTPDESTSNSLTRWEGKSATVGQLMGMRYKGWES GYEDAFVYNLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVYRDNKSVTFAELDVFDLSE ALSAPDVIFH