Protein Info for ECD_00882 in Escherichia coli BL21

Annotation: DUF535 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details PF04393: DUF535" amino acids 48 to 325 (278 residues), 340.8 bits, see alignment E=3.1e-106

Best Hits

Swiss-Prot: 99% identical to YBJX_ECOLI: Uncharacterized protein YbjX (ybjX) from Escherichia coli (strain K12)

KEGG orthology group: K09824, hypothetical protein (inferred from 99% identity to eco:b0877)

Predicted SEED Role

"Virulence factor VirK"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (330 amino acids)

>ECD_00882 DUF535 family protein (Escherichia coli BL21)
MVKSTSCITIDFMNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLL
RSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYAL
LRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPL
AEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRL
QVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIA
EIASKKRAEYRRRYEMLDAIQPQMATMFRG