Protein Info for DZA65_RS22295 in Dickeya dianthicola ME23

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00294: PfkB" amino acids 5 to 296 (292 residues), 248.8 bits, see alignment E=8e-78 TIGR02152: ribokinase" amino acids 7 to 301 (295 residues), 362.8 bits, see alignment E=7e-113 PF08543: Phos_pyr_kin" amino acids 146 to 285 (140 residues), 55.9 bits, see alignment E=4.4e-19

Best Hits

Swiss-Prot: 72% identical to RBSK_ECO57: Ribokinase (rbsK) from Escherichia coli O157:H7

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 96% identity to ddd:Dda3937_02359)

MetaCyc: 72% identical to ribokinase (Escherichia coli K-12 substr. MG1655)
Ribokinase. [EC: 2.7.1.15]

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D5A5 at UniProt or InterPro

Protein Sequence (308 amino acids)

>DZA65_RS22295 ribokinase (Dickeya dianthicola ME23)
MKSGKLVVLGSINADHILNLAQFPRPGETVIGKQYGVAFGGKGANQAVAAGRSGADIEFI
ACVGADDIGERIRQQLIKDRIDVSAVEAISGQTTGVALIFVNGEAENMIGIHAGANAAVM
PDYLNRYQQKIIDASALLMQLESPLETVIAAARLARNNGTKVILNPAPACSLPDELLSLV
DMITPNETEAQILTGVTVETEDDAQRAAQALHDKGIATVLITLGSRGVWLSEQGKGQRIA
GFRVKAVDTIAAGDTFNGALVTALLESRPMVAAIKFAHAAAAIAVTRHGAQPSVPWREEI
DAFLKAQE