Protein Info for DZA65_RS20770 in Dickeya dianthicola ME23

Annotation: DNA uptake porin HofQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details TIGR02515: type IV pilus secretin PilQ" amino acids 32 to 425 (394 residues), 420.5 bits, see alignment E=4.2e-130 PF07660: STN" amino acids 58 to 104 (47 residues), 29.3 bits, see alignment 8.9e-11 PF03958: Secretin_N" amino acids 133 to 195 (63 residues), 52.1 bits, see alignment E=9.4e-18 PF00263: Secretin" amino acids 265 to 425 (161 residues), 162.3 bits, see alignment E=1.2e-51

Best Hits

Swiss-Prot: 50% identical to HOFQ_ECOLI: DNA utilization protein HofQ (hofQ) from Escherichia coli (strain K12)

KEGG orthology group: K02507, protein transport protein HofQ (inferred from 96% identity to ddd:Dda3937_04181)

Predicted SEED Role

"Type IV pilus biogenesis protein PilQ" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CPD7 at UniProt or InterPro

Protein Sequence (434 amino acids)

>DZA65_RS20770 DNA uptake porin HofQ (Dickeya dianthicola ME23)
MKTGRFPGGRLRRYSWLMMVLFSGMLAEARGGEPVSLAFDDVPVQRVLQALADHQQLNLV
VAPGVTGNVSLNLQQVPWQQALDIILRMGQLTIERQGSVMMVYPDAYMKDRQRQQEELAA
KQRQQLPLQNLSVTLQYAEAADVVTSLQSQRGTLLTERGSVTVDKRTNTLLVRDVVAALE
QIRPWIGELDKPLAQVQLAAHIVTISSEHLKALGVNWGLGDAATTGQALQMNNFSVSLPV
ESPAINAGFHLAKLNGRLLDLELMALEQENEVEIIASPRLFTAHQQTASIKQGTEIPYQV
SSGASGSTSIEFKEAVLGMEVTPRILHGGQITLSLLISQNMPGRAIKQGEGSEILAIDKQ
EIQTQVTVQDGETIVLGGIFQQQKNQGERQVPGLGALPGIGQWFRSDNQQHTRRELVIFI
TPTLIQSARRAPAA