Protein Info for DZA65_RS20065 in Dickeya dianthicola ME23

Annotation: HlyD family efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 176 to 193 (18 residues), see Phobius details PF13437: HlyD_3" amino acids 209 to 280 (72 residues), 23.8 bits, see alignment E=6.5e-09 amino acids 304 to 402 (99 residues), 28.1 bits, see alignment E=2.9e-10 PF13533: Biotin_lipoyl_2" amino acids 210 to 254 (45 residues), 31.2 bits, see alignment 1.5e-11

Best Hits

KEGG orthology group: None (inferred from 93% identity to ddc:Dd586_3670)

Predicted SEED Role

"Probable membrane-fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4C724 at UniProt or InterPro

Protein Sequence (439 amino acids)

>DZA65_RS20065 HlyD family efflux transporter periplasmic adaptor subunit (Dickeya dianthicola ME23)
MSNTSPVSGERIFARFLDIERQARSADTAEALAYCIVNDSQTLFGFRHAALVINGTVRAV
TGVTQPAPHAPFVAFIERACAQLQRGRQHEQCAVVEAASLDNQSRNDWLALSAPEVLWAP
LKDRQGRRFGGIWYAREQPWQHAEQLLVEQLADAFSHAWLALEPQPVWRRTRRRWKLIIP
CLLVVGGLFIPVRQSVLAPAEVIPLNGRVVAAPLDGVIQAFAVQPNQSVRKGDLLVRVDD
TTLKAQADVAERALNVAEAEYRASSQRAFQDADSKARLDFLAAQVAQKRAERDYANALLS
RTEIRAERDGIAVFADAERWTGKPVRTGERLMDLADPASVSLRIELDVGDAIRLEPDAPI
TLFLDSDPLTPHGALLDRIAYESEQTPAGNLAYRLDARFTGEPPRIGLRGTAKVSGEQVP
LAVYLFRRPLAVLRQSVGL