Protein Info for DZA65_RS20060 in Dickeya dianthicola ME23

Annotation: HlyD family efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 transmembrane" amino acids 105 to 123 (19 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details amino acids 212 to 230 (19 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 273 to 293 (21 residues), see Phobius details amino acids 349 to 371 (23 residues), see Phobius details amino acids 373 to 374 (2 residues), see Phobius details amino acids 377 to 397 (21 residues), see Phobius details amino acids 413 to 432 (20 residues), see Phobius details PF02163: Peptidase_M50" amino acids 186 to 284 (99 residues), 35.4 bits, see alignment E=1.1e-12 PF13533: Biotin_lipoyl_2" amino acids 451 to 488 (38 residues), 29.2 bits, see alignment 9.2e-11 PF13437: HlyD_3" amino acids 540 to 621 (82 residues), 28.3 bits, see alignment E=3.9e-10

Best Hits

KEGG orthology group: None (inferred from 91% identity to ddc:Dd586_3669)

Predicted SEED Role

"Peptidase M50"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y4Y8 at UniProt or InterPro

Protein Sequence (702 amino acids)

>DZA65_RS20060 HlyD family efflux transporter periplasmic adaptor subunit (Dickeya dianthicola ME23)
MSRFLPTLRTDLQLVESATGLDGAPQWVLADPVTGRYFKLAPSAIRLLRHWSLRHPKWVL
DAANREPGLPLQDNELEQLLRFLRNHDLIAASDPLQRQGYAIKAAALRVSLWKTLLHQYL
FFRIPLWRPDPVLSRCWPGLQHYGLPLLRIALPLMLLLGGFLVSRDWVRYTHTFPHLFSL
QGMAAFGIALVFAKFIHELGHAFMAKRAGCRVQTMGVAFIVLFPLFYTDVSDAWKLKDRR
ARLLVSAGGILAELMLACVALLAWALLPDGPVRTAAFMLSSATWVTTLVVNLNPLMRFDG
YFLLSDFWRVENLQERAYALCRWRLREALFGYGRPAPHTWSPTMQRRLLIWGYASWVWRF
FLFFGIALVVYHFFIKVLGIVLMLVEIGWFIALPVVKEAYIWWSMRKIAHPVSLLRSGLI
LAAVLVVLLFPWRGSIRVPAVLEAENVSVLYAPLSAQVKTLYATDGQRVTAGEVLLELTS
SDLDYRINIERQRIAVLQQQRQRGAGRQETAGETQVLDRQLAESLARYRGLDAQRQRLSI
TAPQAGQVRDAARDMTEGRWLTTDMPLLRVVEQGAGKVQGYLPEDTLTRAKTGMTGNFIA
DDPAYPRLAVQLTDIAPTGTAWLQQEMLASDRHGPIAVRRDRDHNPQPVQAQYRVRFVVL
EGPFLPPQQPLRGSVMLEGETESILGAVWRRVAALGIRESGF