Protein Info for DZA65_RS18880 in Dickeya dianthicola ME23

Annotation: carbohydrate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01547: SBP_bac_1" amino acids 45 to 330 (286 residues), 60 bits, see alignment E=4.1e-20 PF13416: SBP_bac_8" amino acids 49 to 336 (288 residues), 77.5 bits, see alignment E=1.6e-25

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 97% identity to ddd:Dda3937_03082)

Predicted SEED Role

"ABC transporter, substrate binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CHF6 at UniProt or InterPro

Protein Sequence (436 amino acids)

>DZA65_RS18880 carbohydrate ABC transporter substrate-binding protein (Dickeya dianthicola ME23)
MNRYQHALLFSIMTLGAFASIHAIAAKTQITFLYSDDDPELVHFMEQKVKTFSQNNDHID
VNFVSTGYNALQTQLPMQLAAGLGPDIAKTTQMGLLSYTLDLRPYLADPAGFEKRYGAGI
EKIMRINGVHKDNALPGFVASWTADLPFVNVTLFQQAGVPLPQPGYTLEQLMQASKQVAA
KTGVAIPFTIDRSGFRFSGPAYSYGARYDQDGRINFPDAAAQAWIKDLKRWSDDGIFPRE
MWGAAGGGQYKSMADDFVNGNIVTYFSGNWQLNQFSKQIGNGFDWKMLPAPCKEKCISMG
GATFIMPFKTSKHPKEVAEFMEWLGSDATQREIAERFNIIVGADIPALHYQTKDQHVIDG
LNTARAEIANIPAYVFDWEKMESLGGSELYPIILTRFTQYLNNQVSYDEYLRLTENDVKR
LNQTIAGNRQQQQKTQ