Protein Info for DZA65_RS17575 in Dickeya dianthicola ME23

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 100 to 123 (24 residues), see Phobius details amino acids 135 to 159 (25 residues), see Phobius details amino acids 179 to 197 (19 residues), see Phobius details amino acids 235 to 257 (23 residues), see Phobius details amino acids 286 to 308 (23 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 5 to 76 (72 residues), 55.5 bits, see alignment E=6.5e-19 PF00528: BPD_transp_1" amino acids 114 to 313 (200 residues), 128.6 bits, see alignment E=2.3e-41

Best Hits

Swiss-Prot: 38% identical to Y1092_BRUSU: Putative peptide transport system permease protein BRA1092/BS1330_II1084 (BRA1092) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 99% identity to ddc:Dd586_3212)

MetaCyc: 40% identical to nickel ABC transporter membrane subunit NikB (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DUA6 at UniProt or InterPro

Protein Sequence (315 amino acids)

>DZA65_RS17575 ABC transporter permease (Dickeya dianthicola ME23)
MSASYLLKRLLLVIYTLLVVSVLVFSITQLLPADAAVTLLGQHATPEALAAVRARLGLDA
PAWVQYWHWLAAALHGDFGVSMRTNLPVAPTLLTALSRSLLLAACALSLMLLVALPLGVW
AAVRKGKLADVLVSVLSYIGISFPEFVTATLMLLLFADIWQLLPATGYVPLSENLIDGVR
HLVLPSATVAMILVAHVSRMVRSEMVDVLHTDYIRAAWLKGLSRRRILWRHALRNGLLPT
ITIVALDVGYLLGGIVVVEEIFAIPGIGRELIVAVQARDLPTIQGGVMILASTYAVVNFL
ADLAYVMLDKRIHYV