Protein Info for DZA65_RS15880 in Dickeya dianthicola ME23

Annotation: HutD family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 PF05962: HutD" amino acids 9 to 162 (154 residues), 151.7 bits, see alignment E=1.2e-48

Best Hits

Swiss-Prot: 48% identical to VES_CROS8: Protein Ves (ves) from Cronobacter sakazakii (strain ATCC BAA-894)

KEGG orthology group: K09975, hypothetical protein (inferred from 84% identity to ddd:Dda3937_01672)

Predicted SEED Role

"Conserved hypothetical protein (perhaps related to histidine degradation)" in subsystem Histidine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D7F1 at UniProt or InterPro

Protein Sequence (182 amino acids)

>DZA65_RS15880 HutD family protein (Dickeya dianthicola ME23)
MHIFSLETLPVSRWKNGGGETREICRIPSDEPDGDFAWRASIATIERDGDFSCFPGVDRV
IALLSGDGVDLCGDGWRHRLTLHQPFAFAGEQAISARLCGGVSLDFNIMVDRRCCRAEVT
VVSGTTSWTPDTAGVAYVLAGHWRTDTHRLTSGEGAWWRSSGACWTPDDENAVLLLTAIH
AR