Protein Info for DZA65_RS15675 in Dickeya dianthicola ME23

Annotation: type II secretion system ATPase GspE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 TIGR02533: type II secretion system protein E" amino acids 15 to 495 (481 residues), 707.5 bits, see alignment E=4.2e-217 PF00437: T2SSE" amino acids 126 to 392 (267 residues), 374.8 bits, see alignment E=1e-116

Best Hits

Swiss-Prot: 97% identical to GSPE2_DICD3: Type II secretion system protein E (outE) from Dickeya dadantii (strain 3937)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 97% identity to ddd:Dda3937_02416)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CK64 at UniProt or InterPro

Protein Sequence (498 amino acids)

>DZA65_RS15675 type II secretion system ATPase GspE (Dickeya dianthicola ME23)
MSDQPVNTHELRPVLPFSFARAQQILLLQDESATAAEVVCVPGTPASALLEARRVAGVPL
TVSQVSPEEFERQLVMRYQRDSEEARRLMEDIGNDIDFYTLAEELPDSDDLLDGEDDAPI
IRLINAMLTEAIKHKASDIHIETFERHLLIRFRIDGVLREILRPQRQLASLLVSRIKVMA
KLDIAEKRVPQDGRMALRIGGRAIDVRVSTLPSNYGERVVLRLLDKNSVRLDLETLGMAE
HHRRQVDTLIHRPHGIILVTGPTGSGKSTTLYAALSRLNSAERNIMTVEDPIEYELEGIG
QTQVNPKVDMTFARGLRAILRQDPDVVLVGEIRDGETAQIAVQASLTGHLVLSTLHTNSA
LGALSRLQDMGIEPFLLSTSLLGVLAQRLVRTLCPSCRQPYVIDDEQAKQTGLAAGTTLY
HPGGCEKCNYSGYRGRTGIHELLLIDDVVRTAIHSGESELGIARMLGDKRVTIRQDGLDK
VLAGVTTWEEVVRVTKEE