Protein Info for DZA65_RS15645 in Dickeya dianthicola ME23

Annotation: type II secretion system minor pseudopilin GspK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF21687: T2SSK_1st" amino acids 102 to 244 (143 residues), 101.9 bits, see alignment E=3.3e-33 PF03934: T2SSK" amino acids 250 to 309 (60 residues), 59.2 bits, see alignment E=4.3e-20

Best Hits

Swiss-Prot: 85% identical to GSPK_DICCH: Type II secretion system protein K (outK) from Dickeya chrysanthemi

KEGG orthology group: K02460, general secretion pathway protein K (inferred from 92% identity to ddd:Dda3937_02422)

Predicted SEED Role

"General secretion pathway protein K"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D040 at UniProt or InterPro

Protein Sequence (359 amino acids)

>DZA65_RS15645 type II secretion system minor pseudopilin GspK (Dickeya dianthicola ME23)
MSRRQRGVALLIVMLMLALMVTIAATITERSGKAWQRTSNLLNRTQARWYALGAEALISS
VLQRDAQASPESTFVGQPWSKVDHQMMADGSEIRAQVMDGQACLNLNALSPAKTPAPNTA
SGNNNTGNTNTDNTNTGTSNTGTNNPSPPSKGGNPEQGPYAAQVFRQLLMVLGEDPKQAE
RVTDAVRDWLDEDSEPLMNGAEDDSYVNFHPGNQRMTDVTELRSVMGVDAALYRRLLPYV
CVLPVDKLVLNVNTLTPESAPLLSALFMGEMSTEMAERVLQQRPPQGWRNLNDFMGLSAL
PENAKTGIRQVLAIKSDWFFADIQIRVDDSEFYQRSLFHRGKQIEVVQRQYGGYRTVNP