Protein Info for DZA65_RS14705 in Dickeya dianthicola ME23

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 186 to 207 (22 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 1 to 181 (181 residues), 121 bits, see alignment E=8.6e-39 PF02203: TarH" amino acids 1 to 170 (170 residues), 94.2 bits, see alignment E=1.8e-30 PF00672: HAMP" amino acids 205 to 256 (52 residues), 43.1 bits, see alignment 8.4e-15 PF00015: MCPsignal" amino acids 320 to 475 (156 residues), 182.2 bits, see alignment E=1.6e-57

Best Hits

KEGG orthology group: K05874, methyl-accepting chemotaxis protein I, serine sensor receptor (inferred from 87% identity to dze:Dd1591_1453)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y010 at UniProt or InterPro

Protein Sequence (532 amino acids)

>DZA65_RS14705 methyl-accepting chemotaxis protein (Dickeya dianthicola ME23)
MKISTRLWSFTGMLSLGILIMGAIGMFTAEKANQSLKTVYEDRTVVLAHLEKLEWLTQRN
RVLIMDMLLLPNAANKQQRIEELSQNVAQIDRVWIDYRSTYLTPEETRLAGQFADNLQRY
QREGVQPTDAAIRAGQMEQAIRLYDEKVSPLEKKGHTLLSQLVTLQVDVAKDEYTSSVQR
YQWLKALAMMAVLAGIAGAVVFGWLMVRNIVRSLAQAQAAAEAVADGDLTYPINASGRDE
IATVLNALSHMQSSLTRIVGQVRHGAESVGVASGEIAHGNHDLSARTESQASALEQTAAS
MEQLSATVKQNADNARQANQLAQTASQVAEQGGEVVTQVVGTMREINDSAQRIADIIGVI
DSIAFQTNILALNAAVEAARAGEQGRGFSVVAGEVRALAQRSAESAREIKTLISTSVERI
ESGSTLADTAGHTMLEVVNSIRRVTDIMGEISSASGEQSSGVSQVGEAVVSMERTTQQNA
ALVEEMAAAAGSLNSQAAELVQAVGVFRLSDRAPGVRPDTRVEERELLLGYQ