Protein Info for DZA65_RS14280 in Dickeya dianthicola ME23

Annotation: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 52 (22 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 151 to 174 (24 residues), see Phobius details TIGR00560: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase" amino acids 3 to 180 (178 residues), 212.6 bits, see alignment E=3.3e-67 PF01066: CDP-OH_P_transf" amino acids 3 to 166 (164 residues), 126.9 bits, see alignment E=4.6e-41

Best Hits

Swiss-Prot: 87% identical to PGSA_YERE8: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: K00995, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC: 2.7.8.5] (inferred from 98% identity to dze:Dd1591_1520)

MetaCyc: 81% identical to CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Escherichia coli K-12 substr. MG1655)
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [EC: 2.7.8.5]

Predicted SEED Role

"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XZS6 at UniProt or InterPro

Protein Sequence (182 amino acids)

>DZA65_RS14280 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Dickeya dianthicola ME23)
MRFNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAGIFVFAAVTDWFDGFLARRWKQTT
RFGAFLDPVADKVMVAVALVLVAEHYHSWWITLPAATMIAREIIISALREWMAELGKRSS
VAVSWIGKIKTTAQMVALVGLLWRPERMVEAAGVAALYVAAVLTFWSMFQYLSAAWRDLL
EH