Protein Info for DZA65_RS13770 in Dickeya dianthicola ME23

Annotation: HAMP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 190 to 210 (21 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 5 to 173 (169 residues), 49.3 bits, see alignment E=6.8e-17 PF00672: HAMP" amino acids 209 to 258 (50 residues), 17.7 bits, see alignment 5.5e-07 PF00015: MCPsignal" amino acids 325 to 479 (155 residues), 164.5 bits, see alignment E=3.2e-52

Best Hits

KEGG orthology group: None (inferred from 92% identity to ddd:Dda3937_00027)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4C185 at UniProt or InterPro

Protein Sequence (554 amino acids)

>DZA65_RS13770 HAMP domain-containing protein (Dickeya dianthicola ME23)
MRFSNLKIGYRLAIGFSFLIVMLLFAGAVALSSLSDFNRKMDYTVSEIYPMTAKGNRLID
ELNNALLGQQLILMLDSDSDIKRENEEIKGYSAEITALLADLSKNVKDARSASLLRDIQQ
IRSEYSVSGNKLMDLASRGNKQDAVAELINVSLALQQKYKTKVAEFIDYQDDQMMAAREA
VQQNYTYIRMILWLVFIISIVAGGLIAWWITRSVTQPLQEALMLAEKVAKGDLTTEASAC
AQDETGKLLQSLYEMNDSLRNIVSQVRDGAETISSAASQIAAGNQDLSARTEEQASSLEQ
TAASIEQLTATIKNTAANTEHAASLAGQASDIVRQSGEMMANVTREMREIRSGSQRMAEI
IGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRALAQRSANSAKEIKELIDNS
VQKIQDGMSLVENTEQTMGAVIDNAHNTDGVINEIAKASLEQSEGINQINLAIGQIDTTT
QQNAALVEESAAAALSLQEQAQTLAKTVSVFKLNSNRSDKGTTRRQPGGKGLALAGLPGA
KDANVSDTPEWAPF