Protein Info for DZA65_RS13500 in Dickeya dianthicola ME23

Annotation: vitamin B12 ABC transporter permease BtuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 23 to 23 (1 residues), see Phobius details transmembrane" amino acids 24 to 44 (21 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 152 to 175 (24 residues), see Phobius details amino acids 195 to 221 (27 residues), see Phobius details amino acids 240 to 268 (29 residues), see Phobius details amino acids 280 to 300 (21 residues), see Phobius details amino acids 308 to 329 (22 residues), see Phobius details PF01032: FecCD" amino acids 29 to 330 (302 residues), 271 bits, see alignment E=6.1e-85

Best Hits

Swiss-Prot: 74% identical to BTUC_PECAS: Vitamin B12 import system permease protein BtuC (btuC) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K06073, vitamin B12 transport system permease protein (inferred from 96% identity to ddd:Dda3937_04344)

MetaCyc: 67% identical to vitamin B12 ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-5-RXN [EC: 7.6.2.8]; 7.6.2.8 [EC: 7.6.2.8]

Predicted SEED Role

"Vitamin B12 ABC transporter, permease component BtuC" in subsystem Coenzyme B12 biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XZU7 at UniProt or InterPro

Protein Sequence (333 amino acids)

>DZA65_RS13500 vitamin B12 ABC transporter permease BtuC (Dickeya dianthicola ME23)
MQLTPVRYTQLKQQQRRRDRQRLLGLWLLLAVGVAMSLCAGERWIGPTHWLDSDSSLFIW
QLRLPRTLAVMLVGAGLAMGGAVMQAVFDNPLAEPGLLGVSSGAGVALVLAVLIGQGMLP
VWSLSLCAIAGALLVTLMLLRFSRVGVSNARLLLIGVALGIICSALMTWAVYFSTSLDLR
QLMYWMMGGFSGIDWRYGGLMLLMLPLLVWLACCGGVLNQLALGELAARQLGVAVFYWRN
LLVLVMGALVGISVALAGVIGFVGLVIPHILRLCGLTDQRYLLTGCGLAGAVVLMLADTL
ARTLLATAELPVGVVTATLGAPWFIWLLLRHQA