Protein Info for DZA65_RS13010 in Dickeya dianthicola ME23

Annotation: 2-keto-3-deoxygluconate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 103 to 127 (25 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 170 to 187 (18 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details TIGR00793: 2-keto-3-deoxygluconate transporter" amino acids 1 to 314 (314 residues), 604.5 bits, see alignment E=2.7e-186 PF03812: KdgT" amino acids 3 to 312 (310 residues), 375.4 bits, see alignment E=1.3e-116

Best Hits

Swiss-Prot: 93% identical to KDGT_DICCH: 2-keto-3-deoxygluconate permease (kdgT) from Dickeya chrysanthemi

KEGG orthology group: K02526, 2-keto-3-deoxygluconate permease (inferred from 95% identity to dze:Dd1591_1740)

MetaCyc: 90% identical to 2-dehydro-3-deoxy-D-gluconate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-113

Predicted SEED Role

"2-keto-3-deoxygluconate permease (KDG permease)" in subsystem D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XZL3 at UniProt or InterPro

Protein Sequence (337 amino acids)

>DZA65_RS13010 2-keto-3-deoxygluconate transporter (Dickeya dianthicola ME23)
MHIKRSIETIPGGMMLVPLFLGALCHTFAPGAGKYFGSFTNGLISGTVPILAVWFFCMGA
SIRLSATGTVLRKSGTLVVTKIAVAWVVAAVASRILPEHGVEAGFFAGLSTLALVAAMDM
TNGGLYASVMQQYGTKEESGAFVLMSLESGPLMTMVILGTAGIASFEPHVFVGAVLPFLV
GFVLGNLDPELREFFSRSVQTLIPFFAFALGNTIDLSVIGQTGFLGVMLGVAVIIITGIP
LMVADKLLGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPAAPAATTLVATSVIVTSV
LVPIITAMWSKRVKGGDGTVPQADDEQDKVEQQAVRH