Protein Info for DZA65_RS12860 in Dickeya dianthicola ME23

Annotation: zinc transporter ZntB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 transmembrane" amino acids 270 to 290 (21 residues), see Phobius details amino acids 302 to 322 (21 residues), see Phobius details PF01544: CorA" amino acids 42 to 324 (283 residues), 234.8 bits, see alignment E=6.8e-74

Best Hits

Swiss-Prot: 77% identical to ZNTB_PECCP: Zinc transport protein ZntB (zntB) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 96% identity to ddd:Dda3937_03137)

MetaCyc: 62% identical to Zn2+:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-346

Predicted SEED Role

"Zinc transport protein ZntB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CNJ3 at UniProt or InterPro

Protein Sequence (328 amino acids)

>DZA65_RS12860 zinc transporter ZntB (Dickeya dianthicola ME23)
MEVTESKAIWHTGAVFTCQLDGRGGILPLVESGLGEEAVLPAWLHLDSTQSASVRWLHET
SLLPDSVRNALAGDSARPRVVRLGEGTLVTLRSINYNPDARPDELVAIRVFITDRLIVST
RRRKVAAIDEVMSDLKEGNGPATSGDWMVSIAEALTDHTSEFIDELHEKIIDLEDALLEQ
RIPPRGELALIRKQLIVLRRYMTPQRDIFSRLSGEKFGWMQDDDRRRMQEIAERLGRGLE
DLDASIARTTVIADEITTLMTDAMNRRTYTMSLLAMVFLPTTFLTGLFGVNLGGIPGSNS
GIGFGVFCLLLVLLVSGVAWWLKRSKWL