Protein Info for DZA65_RS11245 in Dickeya dianthicola ME23

Annotation: type I secretion system permease/ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 56 to 78 (23 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 255 to 281 (27 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 15 to 556 (542 residues), 827.7 bits, see alignment E=2.2e-253 PF00664: ABC_membrane" amino acids 25 to 281 (257 residues), 54.8 bits, see alignment E=1.2e-18 PF00005: ABC_tran" amino acids 347 to 494 (148 residues), 111.7 bits, see alignment E=4.2e-36

Best Hits

Swiss-Prot: 58% identical to APRD_PSEAE: Alkaline protease secretion ATP-binding protein AprD (aprD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K12536, ATP-binding cassette, subfamily C, bacterial HasD (inferred from 98% identity to ddd:Dda3937_01651)

Predicted SEED Role

"ABC-type protease exporter, ATP-binding component PrtD/AprD" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XXD8 at UniProt or InterPro

Protein Sequence (575 amino acids)

>DZA65_RS11245 type I secretion system permease/ATPase (Dickeya dianthicola ME23)
MNASSERDRSLFGVLRQFRRSFWSVGIFSAVINVLMLAPSVYMLQVYDRVLASGNGITLL
MLTLLMAGLCAFMGALEWVRSLLVVRLGTRIDLALNQDVFNAAFARNLEAGDGRAGLALT
DLTLLRQFITGNALFAFFDVPWFPLFLLVLFLLHPWLGMLALGGTVVLVALAWLNQRLTN
QPLAEANQQSQQATHLADAQLRNADVIEAMGMLGNLRRRWLARHYRFISLQNLASERAAA
VGGASKYSRIALQSLMLGLGALLAIDGKITPGMMIAGSILVGRVLSPIDQLIGVWKQWSS
ARIAWQRLTRLIAAYPPRPAAMALPAPEGHLSVEQLSLRPAQGNARLQNIHFSLQAGETL
VILGASGSGKSSLARLLVGAQSPTQGKVRLDGADLNQVDKSTFGPTIGYLPQDVQLFKGT
LAENIARFGDADPKKVVAAARLAGVHELILSLPTGYDTELGEGGSGLSGGQRQRIGLARA
MYGDPCLLILDEPNASLDSEGDQALMQAIVALQKRGATVVLITHRPALTTLAQKILILHE
GNQQRMGLARDVLTELQQRSAANQARMNPTAAMPQ