Protein Info for DZA65_RS10730 in Dickeya dianthicola ME23

Annotation: PrkA family serine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 644 PF08298: AAA_PrkA" amino acids 19 to 380 (362 residues), 605.7 bits, see alignment E=2.9e-186 PF06798: PrkA" amino acids 382 to 636 (255 residues), 244.3 bits, see alignment E=1.7e-76

Best Hits

Swiss-Prot: 94% identical to YEAG_ECOLI: Uncharacterized protein YeaG (yeaG) from Escherichia coli (strain K12)

KEGG orthology group: K07180, serine protein kinase (inferred from 98% identity to ddc:Dd586_2166)

MetaCyc: 94% identical to protein kinase YeaG (Escherichia coli K-12 substr. MG1655)
2.7.11.d,2.7.11.11,2.7.12.1,2.7.11.12,2.7.11.17,2.7.11.1,2.7.11.13,2.7.11.22,2.7.11.21,2.7.11.34,2.7.11.31 [EC: 2.7.11.1, 2.7.11.11, 2.7.11.12, 2.7.11.13, 2.7.11.17, 2.7.11.21, 2.7.11.22, 2.7.11.31, 2.7.11.34, 2.7.11.d, 2.7.12.1]

Predicted SEED Role

"Uncharacterized protein YeaG"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.11.1 or 2.7.11.11 or 2.7.11.12 or 2.7.11.13 or 2.7.11.17 or 2.7.11.21 or 2.7.11.22 or 2.7.11.31 or 2.7.11.34 or 2.7.11.d or 2.7.12.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4C2V0 at UniProt or InterPro

Protein Sequence (644 amino acids)

>DZA65_RS10730 PrkA family serine protein kinase (Dickeya dianthicola ME23)
MNIFDHYRQRYDAAKDEEFTLQEFLTICQQDRSAYVNAAERLLMAIGEPTMVDTALEPRL
SRLFSNRVIARYPAFEEFYGMEEAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLA
ERLKSLMQRVPIYILSANGEHSPVNDHPLSLFNPQEDASILEKEYSIPRRYLGTIMSPWA
AKRLQEFGGDITKFRVVKVWPSILAQLAIAKTEPGDENNQDISALVGKVDIRKLEHFAQN
DPDAYGYSGALCRANQGVMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGIAALPFNGIIL
AHSNESEWVQFRNNKNNEAFLDRVYIVKVPYCLRVSEEVRIYDKLLKNSELSSAPCAPGT
LETLARFSILSRLKDPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMKGLS
TRFAFKILSRVFNFDHSEVAANPVHLFYVLEQQIEREQFPQDVAEKYLEHLKGYLIPKYA
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKI
EKPAGISNPKDFRNEIVNFVLRARASNSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVIS
FNTKTSTEEQKKHDDFVDRMMEKGYTRKQVRLLCEWYLRVRKSS