Protein Info for DZA65_RS10175 in Dickeya dianthicola ME23

Annotation: ComEC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 42 to 63 (22 residues), see Phobius details amino acids 222 to 246 (25 residues), see Phobius details amino acids 259 to 276 (18 residues), see Phobius details amino acids 296 to 316 (21 residues), see Phobius details amino acids 327 to 344 (18 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 393 to 418 (26 residues), see Phobius details amino acids 422 to 423 (2 residues), see Phobius details amino acids 429 to 447 (19 residues), see Phobius details amino acids 467 to 486 (20 residues), see Phobius details TIGR00361: DNA internalization-related competence protein ComEC/Rec2" amino acids 124 to 714 (591 residues), 611.8 bits, see alignment E=1.4e-187 PF03772: Competence" amino acids 200 to 470 (271 residues), 187.5 bits, see alignment E=3.3e-59 TIGR00360: ComEC/Rec2-related protein" amino acids 221 to 404 (184 residues), 129.6 bits, see alignment E=1.5e-41 PF00753: Lactamase_B" amino acids 501 to 674 (174 residues), 89 bits, see alignment E=4.1e-29

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 85% identity to dze:Dd1591_2310)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XX23 at UniProt or InterPro

Protein Sequence (750 amino acids)

>DZA65_RS10175 ComEC family protein (Dickeya dianthicola ME23)
MSLNQLAATLIAGPLLLLILPGLPERHSLVWGLPALWLLKTRFYPIGLVVLGVVWSLYSG
RMILNQVEQFTQRPVTARVSVSSVRFAQADAGQVVVRLWEINGRWVFPPLYARLDAPPQM
TDWCGGQQWETRLRLRPVHSRLNEGGFDRQRWALAKAQPLTGRILSAVVLAPECGLRQRV
VEQAEQQTRSLPWRSIILALAIGEMAVVEDEILDVLRQTGIMHLMAISGLHIVLAALSGW
GVVRVVQCLLPIHWVEHRAPLWCGLCCAWGYVWLAGGNPPAVRAALALSCWTLLRLRGVS
VSSWQVWLWCVALILVSDPLSVLSDSFWLSALAVAALIFWYQWAPLPPHLQRPKRWIWLR
GLHLQTGIILLLMPLQVLLFHGVSLSSLPANLWAVPLVSFITTPLILLALPLMVIPVAAH
GLWWLADRSLALVFLPLQAMPPGWLSLGENAVPYSVAGWLAVIVWRFAWWRTYPLSLLAL
VLVMLLRPKSPAPSWRVDMLDVGHGLAVVIERQGKAWLYDTGPGWDGGNMADREILPYLK
WRGLQLEGIILSHSHLDHRGGLETVQRAFSTVPVYSPLLDQGHRPCIQGERWRWQGLTFS
VIWPPLQVREAGNHDSCVVRVDDGRHRVLLTGDLEHEDEAMLLRTQREMLAADILQVPHH
GSTTSSSPPFLRAVGAGQALSSNSRYNPWRLPAVSVVRRYRQRGDNWRDTASDGQLSVHF
FDEGIEMLRYRGEISPRWYHQWFGALRDNE