Protein Info for DZA65_RS09640 in Dickeya dianthicola ME23
Annotation: oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 68% identical to HCXA_ECOLI: Hydroxycarboxylate dehydrogenase A (hcxA) from Escherichia coli (strain K12)
KEGG orthology group: K08317, uncharacterized oxidoreductase [EC: 1.1.-.-] (inferred from 96% identity to ddd:Dda3937_04555)Predicted SEED Role
"Glycerol dehydrogenase (EC 1.1.1.6)" in subsystem Respiratory dehydrogenases 1 (EC 1.1.1.6)
MetaCyc Pathways
- glycerol degradation II (1/2 steps found)
- glycerol degradation V (1/2 steps found)
- glycerol degradation to butanol (11/16 steps found)
- superpathway of glycerol degradation to 1,3-propanediol (1/4 steps found)
KEGG Metabolic Maps
- 1- and 2-Methylnaphthalene degradation
- Benzoate degradation via CoA ligation
- Bisphenol A degradation
- Ethylbenzene degradation
- Glycerolipid metabolism
- Limonene and pinene degradation
- Naphthalene and anthracene degradation
- Retinol metabolism
- gamma-Hexachlorocyclohexane degradation
Isozymes
Compare fitness of predicted isozymes for: 1.1.-.-, 1.1.1.6
Use Curated BLAST to search for 1.1.-.- or 1.1.1.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A385XWU8 at UniProt or InterPro
Protein Sequence (362 amino acids)
>DZA65_RS09640 oxidoreductase (Dickeya dianthicola ME23) MSTTDIRVQVGPANYFSFPGAIDKLSEFYPDEVLARALWIHGERALAATCAYLPAAFSAP TARSASFSAHCSENEIARLTAAAGDDRTVVIGVGGGAVLDTAKVVARRLGLPLVAIPTIA ATCAAWTPLSVWYNDAGQALRFEIFHDANHLVLVEPRILLAAPVEYLLAGIGDTLAKWYE AVVLSPQPETLSLTVRLGVQTAQDIRDVLLNQSESALKAARNATLNQDFLDVVDAIIAGG GMVGGLGERYTRVAAAHAVHNGLTVLPQTAHFLHGTKVAYGILVQCALLGQTETLRQLKA AFRVFGLPVSLAELDVDMTDETALQAVIARTLQAGESIHYLPGPLDADTLLTAFQTVERA ND