Protein Info for DZA65_RS09560 in Dickeya dianthicola ME23

Annotation: sugar efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 signal peptide" amino acids 12 to 13 (2 residues), see Phobius details transmembrane" amino acids 14 to 33 (20 residues), see Phobius details amino acids 51 to 72 (22 residues), see Phobius details amino acids 84 to 101 (18 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 176 to 194 (19 residues), see Phobius details amino acids 219 to 240 (22 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 283 to 302 (20 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 369 to 389 (21 residues), see Phobius details TIGR00899: sugar efflux transporter" amino acids 19 to 392 (374 residues), 614.4 bits, see alignment E=3.8e-189 PF07690: MFS_1" amino acids 21 to 346 (326 residues), 128.8 bits, see alignment E=1.2e-41

Best Hits

Swiss-Prot: 96% identical to SOTA_DICCH: Sugar efflux transporter A (sotA) from Dickeya chrysanthemi

KEGG orthology group: K03291, MFS transporter, SET family, sugar efflux transporter (inferred from 94% identity to dze:Dd1591_2427)

MetaCyc: 69% identical to sugar exporter SetB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-82

Predicted SEED Role

"Sugar efflux transporter B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4C6I4 at UniProt or InterPro

Protein Sequence (393 amino acids)

>DZA65_RS09560 sugar efflux transporter (Dickeya dianthicola ME23)
MTISSARPARRLPNLTSSAFLVIAFLTGIAGALQLPTLSLFLSTEVQVRPFMVGLFYTGS
AVIGIVVSQMLATYSDRQGDRKTLILQCCLLGALACLLYAWNRNYFVLLFIGVLLSSFGS
TANPQLFALAREHTDRTGRGAAMFSSVMRAQISLSWVIGPPVAFALALGFGFPTMYLTAA
VVFVLCGLLVWLLLPSMPKTWVKSAATLESPRQNRRDTLLLFSACTLMWTCNGIYLINMP
LYLVHELQLPEKLAGVMMGTAAGLEIPVMLLAGYLANRLGKRLLMRLAVVAGLMFYAGLT
LLNGSWALLALQLLNAIFIGILAGMGMLYFQDLMPGQAGAATTLFTNTTRVGWIISGSLA
GIVAEVWSYHAGFVIAIAMLAGAAASMWRIRDA