Protein Info for DZA65_RS09480 in Dickeya dianthicola ME23

Annotation: OFA family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 10 to 31 (22 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 166 to 184 (19 residues), see Phobius details amino acids 214 to 235 (22 residues), see Phobius details amino acids 247 to 268 (22 residues), see Phobius details amino acids 280 to 298 (19 residues), see Phobius details amino acids 304 to 330 (27 residues), see Phobius details amino acids 341 to 361 (21 residues), see Phobius details amino acids 367 to 385 (19 residues), see Phobius details PF07690: MFS_1" amino acids 21 to 300 (280 residues), 101 bits, see alignment E=3.4e-33 amino acids 234 to 394 (161 residues), 71.5 bits, see alignment E=3.3e-24

Best Hits

Swiss-Prot: 47% identical to YHJX_ECOLI: Uncharacterized MFS-type transporter YhjX (yhjX) from Escherichia coli (strain K12)

KEGG orthology group: K08177, MFS transporter, OFA family, oxalate/formate antiporter (inferred from 97% identity to ddd:Dda3937_03819)

Predicted SEED Role

"Oxalate/formate antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CMC3 at UniProt or InterPro

Protein Sequence (405 amino acids)

>DZA65_RS09480 OFA family MFS transporter (Dickeya dianthicola ME23)
MNERPVNRSVIIAGTVLAQMGLGTIYTWSLYNQPLVDKFDWPLSSVATTFSLTSFFLAFA
TLFAGRIQERIGIRKLTLIAGLVLGAALMAAAMVSSLPMLWLLVGVVVGFADGAAYITTL
SNLIKWFPNRKGVIAGISVGAYGTGSLVFKYINSALLAQVGVSQTFFWWGVMALLMITGG
AMLLKDAPVQPAQTAAQGGNVNFTVSEMLRRKEAWLLFVVFFTSCMSGLYLIGIAKDIGV
KMAGLDAVTAAGVVSAIAICNTAGRLILGYLSDKVGRLRVLNFTLLVTALAVTVMAFLPL
NAMTFFLCTGAAAFCFGGNITVYPAIVADFFGLKHHSKNYGLIYQGFGLGPLAGSFIAAA
LGGFHSTFIAIALLSVVSLVITLFIQPPKAPHEQGAPLVAQGSHA