Protein Info for DZA65_RS09105 in Dickeya dianthicola ME23

Annotation: peptidase T

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 TIGR01882: peptidase T" amino acids 8 to 405 (398 residues), 327.9 bits, see alignment E=4.4e-102 PF05343: Peptidase_M42" amino acids 143 to 207 (65 residues), 30.6 bits, see alignment E=2.9e-11 PF01546: Peptidase_M20" amino acids 143 to 402 (260 residues), 40.8 bits, see alignment E=3.5e-14 PF07687: M20_dimer" amino acids 209 to 310 (102 residues), 42.7 bits, see alignment E=7e-15

Best Hits

Swiss-Prot: 73% identical to Y1009_YERPE: Peptidase T-like protein YPO1009/y3403/YP_3421 (YPO1009) from Yersinia pestis

KEGG orthology group: K01258, tripeptide aminopeptidase [EC: 3.4.11.4] (inferred from 95% identity to ddd:Dda3937_02906)

Predicted SEED Role

"Tripeptide aminopeptidase (EC 3.4.11.4)" (EC 3.4.11.4)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.4

Use Curated BLAST to search for 3.4.11.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y146 at UniProt or InterPro

Protein Sequence (413 amino acids)

>DZA65_RS09105 peptidase T (Dickeya dianthicola ME23)
MSNTLARQLTDRFYRYLAVTSQSDAAATTLPSTPGQMAMARLLAEELRALGLSQVVCDEH
ATVTAVKPGNTPSAPRIGFITHIDTVDVGLSPDIHPQILRFTGEDLCLNPAQDIWLRVSE
HPEILPYRNQEIIFSDGASVLGADNKAAVTVVMTLLENLRDDPPHGDIVVAFVPDEEIGL
RGAKALDLARFDVDFAYTIDCCELGEVVYENFNAAAAEIRFTGVTAHPMSAKGVLVNPVL
MAHDFISRFDRRHTPEHTEGREGYVWFNDIHANANEAVLKTSIRDFDLTEFAQRKQQIRD
VAAQIAAHYPAGQVSCAIADIYSNISNALGDDRRALDLLFAAMHTLSIAPKVIPMRGGTD
GAALSAKGILTPNFFTGAHNFHSRFEFLPLPSFVKSYQVALTLCLLAARQPSA