Protein Info for DZA65_RS09060 in Dickeya dianthicola ME23

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 transmembrane" amino acids 32 to 51 (20 residues), see Phobius details amino acids 186 to 209 (24 residues), see Phobius details amino acids 236 to 259 (24 residues), see Phobius details amino acids 265 to 288 (24 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 353 to 374 (22 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 18 to 372 (355 residues), 65.8 bits, see alignment E=6e-22 PF12698: ABC2_membrane_3" amino acids 34 to 374 (341 residues), 139.8 bits, see alignment E=1.8e-44 PF01061: ABC2_membrane" amino acids 183 to 345 (163 residues), 75.9 bits, see alignment E=5.2e-25

Best Hits

Swiss-Prot: 74% identical to YBHS_ECO57: Probable multidrug ABC transporter permease YbhS (ybhS) from Escherichia coli O157:H7

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 93% identity to dze:Dd1591_2513)

MetaCyc: 74% identical to ABC exporter membrane subunit YbhS (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-366 [EC: 7.6.2.2]

Predicted SEED Role

"ABC transport system, permease component YbhS"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XW41 at UniProt or InterPro

Protein Sequence (381 amino acids)

>DZA65_RS09060 ABC transporter permease (Dickeya dianthicola ME23)
MPPHIDDTHFSWRRLRALCLKETRQILRDPSSALIAFVIPLLLLFIFGYGINLDSSRLNV
GVLVEQRSAEADSLARAFTGSPYLAVTLSDNRPALIKRMQAGQIRGLLVIPADFAKRLAH
PQDRAPIQVITDGSEPNTAQFVQGYAQGVWQRWQQQYAQDHGGRYQPLIEVQTRYWFNAA
AISRHFIIPGAITIIMTVIGAILTSLVIAREWERGTMEALLSTQVTRTELLFAKLLPYYV
LGMIAMALCVAVAVFVLGVPYRGSLWLLFGISSLFLASTLGMGLLISTLTRNQFNAAMVA
LNAAFLPAVMLSGFIFEIHSMPMLVQAVSYLIPARYFVSTLQTLFLAGNISSVLLMNLLF
LMTSAVFFIGLTAWKTRRRLD