Protein Info for DZA65_RS08545 in Dickeya dianthicola ME23

Annotation: type VI secretion system contractile sheath large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 TIGR03355: type VI secretion protein, EvpB/VC_A0108 family" amino acids 17 to 490 (474 residues), 704.6 bits, see alignment E=3.2e-216 PF05943: VipB" amino acids 66 to 365 (300 residues), 423.1 bits, see alignment E=5.6e-131 PF18945: VipB_2" amino acids 378 to 489 (112 residues), 156.1 bits, see alignment E=3.8e-50

Best Hits

KEGG orthology group: K11900, type VI secretion system protein ImpC (inferred from 99% identity to dze:Dd1591_2806)

Predicted SEED Role

"Uncharacterized protein ImpC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XVU2 at UniProt or InterPro

Protein Sequence (492 amino acids)

>DZA65_RS08545 type VI secretion system contractile sheath large subunit (Dickeya dianthicola ME23)
MSMVEEQAQTSAAGGSSSLLEEIMAQARITPVDEGYNVAKQGIAALVANILDSGNAAEPV
NKALVDSMIVELDKKLSKQIDVILHAQELQELESSWRSLKLLIDRTDFRENIKILLLHAT
KNELLEDFEFAPEITQSGFYKHVYSNGYGQFGGQPVGGVIGDYALTQSSPDIKLMQYVSA
VGAMAHAPFISSVAPTFFGVDSFTDLPSIKDLKSVFEGPAYTKWRSMRESEDARYLGLTA
PRFLARLPYDPVENPIKGFHYKEDISVNHEHYLWGNTAYLMGTAITDSFAKYRWCPNIIG
PQSGGAITDLPVHVYEAMGQLQAKIPTEVLITDRREYEMAEEGFITLTMRKDSDNAAFFS
ANSVQKPKVFANTKEGKEAETNYKLGTQLPYMFIINRLAHYIKVLQREQIGSWKERQDLE
RELNNWIKQYVADQENPPADVRSRRPLRAAQIKVLDVEGEPGWYQVTMAVRPHFKYMGAN
FELSLVGRLDKE