Protein Info for DZA65_RS08325 in Dickeya dianthicola ME23

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00005: ABC_tran" amino acids 19 to 167 (149 residues), 126.3 bits, see alignment E=1.3e-40

Best Hits

KEGG orthology group: K02068, putative ABC transport system ATP-binding protein (inferred from 96% identity to dze:Dd1591_2630)

MetaCyc: 43% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XVW3 at UniProt or InterPro

Protein Sequence (263 amino acids)

>DZA65_RS08325 ATP-binding cassette domain-containing protein (Dickeya dianthicola ME23)
MIRIERLGKRYPGCAQPALENVSLTIPSGAVYGILGRSGAGKSTLIRCLNLLERPTSGRI
LMDDCDIARLSPRALRQQRQRTGMIFQHFNLLHARTVRDNVAVPLEIAGVDRREREARVT
ELLALVGLSDKAPAYPSQLSGGQKQRVGIARALAAQPRYLLCDEATSALDPETTASILAL
LADINRQLGLTIVLITHELEVVKAICDHAALLEQGRVAESGALRTLLADPASRLRQALLP
DLDAERAFLRRHGVEEGELCKVA