Protein Info for DZA65_RS08090 in Dickeya dianthicola ME23

Annotation: DHA2 family efflux MFS transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 36 to 61 (26 residues), see Phobius details amino acids 73 to 98 (26 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details amino acids 223 to 242 (20 residues), see Phobius details amino acids 263 to 285 (23 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details amino acids 324 to 345 (22 residues), see Phobius details amino acids 354 to 377 (24 residues), see Phobius details amino acids 398 to 417 (20 residues), see Phobius details amino acids 427 to 448 (22 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 8 to 409 (402 residues), 268.1 bits, see alignment E=7.3e-84 PF07690: MFS_1" amino acids 12 to 403 (392 residues), 170.4 bits, see alignment E=2.7e-54

Best Hits

KEGG orthology group: None (inferred from 92% identity to dze:Dd1591_2675)

Predicted SEED Role

"Permease of the major facilitator superfamily in achromobactin biosynthesis operon"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CU76 at UniProt or InterPro

Protein Sequence (476 amino acids)

>DZA65_RS08090 DHA2 family efflux MFS transporter permease subunit (Dickeya dianthicola ME23)
MIPRWLVVLNVLLGTTTVSLNNSTLNPALPTFIEVFHIGPLLATWIVAAFMVSMGMTMPL
TGYLGHRLGNKPLYLLGVALFITGSLLGMLADSISLVIAARTVQGIASGLMIPLSLTLIF
SVYPRQERGGITGIWGAIVMLAPALGPLCGGILLEWFNWRALFAMNIPVGALALLMGLVV
LPKTAPGERKPFDMTGYLLVSAGIGLLMVGAGRLHHAAALANPLNILMLLAAAVCLAAFV
RVELRKREPLLNLRIFQLHGYRLSVVIAVVQSVGMFECLVLLPMLVQMVMGYSAIWTGLA
LLCTALFASLFGKVGGSLLDRHGAARVVGVGMLLTALATVGLGMTGAQTSIGAVFGWMML
RGVGLGLSYMPVTTAGLNVLPETLVTQGAAMNNISRRLVSSLAIVVAALYLEFRLAGSGL
AHEAVRAAAISETFIATGLLIVLALPCALRFPTATDEAAANALVAGAAPAGTRELR