Protein Info for DZA65_RS07250 in Dickeya dianthicola ME23

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF00005: ABC_tran" amino acids 33 to 192 (160 residues), 109.5 bits, see alignment E=3.2e-35 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 242 to 328 (87 residues), 70.9 bits, see alignment E=3.7e-24 PF08352: oligo_HPY" amino acids 244 to 307 (64 residues), 62.6 bits, see alignment E=5.4e-21

Best Hits

Swiss-Prot: 47% identical to DPPD_ECO57: Dipeptide transport ATP-binding protein DppD (dppD) from Escherichia coli O157:H7

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein (inferred from 92% identity to ddd:Dda3937_00837)

MetaCyc: 47% identical to dipeptide ABC transporter ATP binding subunit DppD (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CEE1 at UniProt or InterPro

Protein Sequence (339 amino acids)

>DZA65_RS07250 ABC transporter ATP-binding protein (Dickeya dianthicola ME23)
MTLLNVNGLVNVNGLLNVNGLTLENRQGIRLVDAVSFSLRKGEMLGLVGESGSGKTLTCR
ALMRLLPGAGLRIAAGEVWLNGQDVMQLNDAQMTNVRGRQLGMIFQNPASHLNPVMTIGE
QIAESRRLHFGSRRRAARDEAIALLQQVGIPDPVRRAGHYPHEFSGGMRQRAMIAVALAC
EPQILIADEPTTALDVTVQMQILRLLAQLRQQLGIAIIMITHDLGVVAQTCDRMAVMYGG
RLCELGDKRALLSSPHHPYTRALIACQPMQAGDSGPLRTLPGQPPLPEQFGDGCRFEPRC
ARAGERCRRQTPRLTGSCADTARQLACHYPLVEQEGEAG