Protein Info for DZA65_RS06985 in Dickeya dianthicola ME23

Annotation: galactose-1-phosphate uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 TIGR00209: galactose-1-phosphate uridylyltransferase" amino acids 2 to 347 (346 residues), 650.6 bits, see alignment E=2.6e-200 PF01087: GalP_UDP_transf" amino acids 5 to 176 (172 residues), 236 bits, see alignment E=4.3e-74 PF02744: GalP_UDP_tr_C" amino acids 182 to 345 (164 residues), 244.7 bits, see alignment E=4.2e-77

Best Hits

Swiss-Prot: 82% identical to GAL7_ECOLI: Galactose-1-phosphate uridylyltransferase (galT) from Escherichia coli (strain K12)

KEGG orthology group: K00965, UDPglucose--hexose-1-phosphate uridylyltransferase [EC: 2.7.7.12] (inferred from 97% identity to ddd:Dda3937_03997)

MetaCyc: 82% identical to galactose-1-phosphate uridylyltransferase (Escherichia coli K-12 substr. MG1655)
UDP-glucose--hexose-1-phosphate uridylyltransferase. [EC: 2.7.7.12]

Predicted SEED Role

"Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)" in subsystem Lactose and Galactose Uptake and Utilization (EC 2.7.7.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.10 or 2.7.7.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XV66 at UniProt or InterPro

Protein Sequence (350 amino acids)

>DZA65_RS06985 galactose-1-phosphate uridylyltransferase (Dickeya dianthicola ME23)
MAYFDPVEHPHRRYNPLTGQWVLVSPHRAKRPWQGQQESVSSDPLASHDPSCFLCPGNTR
ATGDTNPDYQDTFVFTNDFAALMTDTPAAPENSDPLMRCQSARGTSRVICFSPDHSKTLP
ELPLGALEQVVATWQQQSAELGQTYPWVQVFENKGAAMGCSNPHPHGQIWANDFLPNEAE
REDRQQRDYFQQYGSPLLVDYLQRELQDGARHVVETEHWLAVVPYWAAWPFETLLLPKAH
VLRLPDITTQQRQDLALALKKLTSRYDNLFQTSFPYSMGWHGAPFTDGDHPHWQLHAHFY
PPLLRSATVRKFMVGYEMLAETQRDLTAEQAAERLRAVSDIHYRDSGVQA