Protein Info for DZA65_RS04765 in Dickeya dianthicola ME23

Annotation: restriction endonuclease subunit S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 PF01420: Methylase_S" amino acids 67 to 200 (134 residues), 38.2 bits, see alignment E=8.7e-14 amino acids 242 to 424 (183 residues), 48.2 bits, see alignment E=7.7e-17

Best Hits

Predicted SEED Role

"Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XVZ5 at UniProt or InterPro

Protein Sequence (449 amino acids)

>DZA65_RS04765 restriction endonuclease subunit S (Dickeya dianthicola ME23)
MVSEQQSGTAGKDVPAGFKLTEVGVIPQDWEVVPFFDVVSIVSGQVSPICEPYSSMILIA
PDHIETGTGRLISTQSAKEQNAISGKYIFHSGDTIYSKIRPYLRKAIYADFDGLCSADMY
PLRPKEGIEPKYILPLVLGNRFSKYAESVSVRSGIPKINRTEIADFLFVIPSQREEQTAI
ANVLFDTEALITALEQLIAKKQAIKTATMQQLLTGKIRLPQFALRDDGAAKGYKKSEAGN
IPEDWYTSTILDIVTHIIDYRGRTPKKLGMDWGNGNIVALSAGNVKKGYIDFLSECYFGS
DELYNRWMTSGTPKRNDIVFTMEAPLGNAALIPDDKKYILSQRTILLQINEERFTPIFIL
QVLLSDFFQSYIYDCATGSTAQGIKRSIFEKLYIAAPKNREEQTAIASILSDMDKDIQTL
QQRLDKTRQLKQGMMQELLTGKTRLIERN